ÍÎÂÎÑÒÈ ÀÑÑÎÖÈÀÖÈß ÎÁÐÀÇÎÂÀÍÈÅ ÍÀÓÊÀ ÁÈÁËÈÎÒÅÊÀ ÍÎÐÌÀÒÈÂÛ ÎÁÚÅÄÈÍÅÍÈß ÎÑÍÀÙÅÍÈÅ ÊÀ×ÅÑÒÂÎ
Tan KL, Lim GC, Boey KW
Efficacy of phototherapy for hyperbilirubinaemia in
infants with the respiratory distress syndrome
J Paediatr Child Health 31 (2): 127-129, Apr 1995
SINGAPORE
OBJECTIVE: To evaluate the efficacy of phototherapy for
hyperbilirubinaemia in preterm infants with and without the
respiratory distress syndrome (RDS).
METHODOLOGY: Prospective cohort study of preterm infants cared
for at Kandang Kerbau Hospital, Singapore: 170 with RDS and 477
without RDS, sepsis or other complications (control group)
presenting with non-haemolytic hyperbilirubinaemia at about the
same time were exposed to daylight phototherapy when bilirubin
concentrations exceeded 255 mumol/L or 222 mumol/L if < 48 h
of age. Bilirubin values were monitored 6-hourly during exposure,
and daily for at least 2 days post-phototherapy.
RESULTS: The infants were comparable in birthweight, gestational
age, postnatal age, haemoglobin, haematocrit and bilirubin
values, at start. The response to phototherapy of the infants
with RDS was comparable to that of the well preterm infants; the
duration of exposure was 50.1 +/- 1.6 (mean +/- s.e.m.) versus
50.1 +/- 1.4 h, 24-hour decline rate 25.71 +/- 1.29% versus 26.32
+/- 0.65, and overall decline rate 0.96 +/- 0.03%/h versus 0.95
+/- 0.02%/h.
CONCLUSION: The presence of RDS did not affect the efficacy of
phototherapy for neonatal hyperbilirubinaemia in preterm infants.